環境

学術研究成果リスト

Detail of Grant Awarded Academic Researches

Project

Identification of conjugative plasmids harboring antibiotic resistance genes in the Tama River flowing through mega city Tokyo

Academic
Research
No.355
Principal
Investigator
Masaki SHINTANI
Affiliation Graduate School of Integrated Science and Technology, Shizuoka University
Research
Summary

Understanding the mechanism of drug resistance gene transmission by conjugative plasmids is important for preventing the spread of multidrug-resistant bacteria. Exogenous plasmid capturing was performed with microbes in the Tama River. Broad host range plasmids belonging to new types of IncP-1 and PromA groups were successfully obtained. Some IncP-1 plasmids possessed multi-drug resistance genes, including carbapenem-resistance gene. These results suggest that several kinds of plasmids are involved in the spread of antibiotic resistance genes in the Tama river.


Collaborators

Hideo DORA
Ryota MORIUCHI

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